PLoS genetics
Journal
Overview
publication venue for
-
Correction: The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3'-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis.
2024
-
Correction: Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools.
2016
-
Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis..
19.
2023
-
The RNA Binding Protein DND1 is Elevated in a Subpopulation of Pro-Spermatogonia and Targets Chromatin Modifiers and Translational Machinery During Late Gestation..
19.
2023
-
Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative..
18.
2022
-
Ustilago maydis telomere protein Pot1 harbors an extra N-terminal OB fold and regulates homology-directed DNA repair factors in a dichotomous and context-dependent manner..
18.
2022
-
RB depletion is required for the continuous growth of tumors initiated by loss of RB..
17.
2021
-
Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish..
17.
2021
-
Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations..
17.
2021
-
Tissue specificity-aware TWAS (TSA-TWAS) framework identifies novel associations with metabolic, immunologic, and virologic traits in HIV-positive adults..
17.
2021
-
Structure-function analysis of fission yeast cleavage and polyadenylation factor (CPF) subunit Ppn1 and its interactions with Dis2 and Swd22..
17.
2021
-
The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP..
16.
2020
-
Independent validation of experimental results requires timely and unrestricted access to animal models and reagents..
16.
2020
-
In vivo modeling of metastatic human high-grade serous ovarian cancer in mice..
16.
2020
-
An osteocalcin-deficient mouse strain without endocrine abnormalities..
16.
2020
-
Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone..
16.
2020
-
Loss-of-function tolerance of enhancers in the human genome..
16.
2020
-
Integrative comparison of the genomic and transcriptomic landscape between prostate cancer patients of predominantly African or European genetic ancestry..
16.
2020
-
Bacillus subtilis PgcA moonlights as a phosphoglucosamine mutase in support of peptidoglycan synthesis..
15.
2019
-
Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies..
15.
2019
-
Functional robustness of adult spermatogonial stem cells after induction of hyperactive Hras..
15.
2019
-
Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing..
15.
2019
-
Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation..
15.
2019
-
Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk..
14.
2018
-
rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline..
13.
2017
-
Crosstalk between the tricarboxylic acid cycle and peptidoglycan synthesis in Caulobacter crescentus through the homeostatic control of α-ketoglutarate..
13.
2017
-
Evidence for the evolutionary steps leading to mecA-mediated β-lactam resistance in staphylococci..
13.
2017
-
Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis..
13.
2017
-
Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival..
12.
2016
-
Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape..
12.
2016
-
Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I..
12.
2016
-
Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's Disease..
12.
2016
-
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes..
12.
2016
-
Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions..
12.
2016
-
Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools..
12.
2016
-
Preferential Allele Expression Analysis Identifies Shared Germline and Somatic Driver Genes in Advanced Ovarian Cancer..
12.
2016
-
dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest..
11.
2015
-
Mre11 and Blm-Dependent Formation of ALT-Like Telomeres in Ku-Deficient Ustilago maydis..
11.
2015
-
Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality..
11.
2015
-
Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia..
11.
2015
-
The Human Blood Metabolome-Transcriptome Interface..
11.
2015
-
A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum..
11.
2015
-
The chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers..
11.
2015
-
The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis..
11.
2015
-
A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations..
10.
2014
-
Analysis of Candida albicans mutants defective in the Cdk8 module of mediator reveal links between metabolism and biofilm formation..
10.
2014
-
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex..
10.
2014
-
Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation..
10.
2014
-
An essential nonredundant role for mycobacterial DnaK in native protein folding..
10.
2014
-
The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability..
10.
2014
-
SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates..
10.
2014
-
DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers..
10.
2014
-
Sugar and chromosome stability: clastogenic effects of sugars in vitamin B6-deficient cells..
10.
2014
-
Validation and genotyping of multiple human polymorphic inversions mediated by inverted repeats reveals a high degree of recurrence..
10.
2014
-
Reconstructing Native American migrations from whole-genome and whole-exome data..
9.
2013
-
The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast..
9.
2013
-
Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression..
9.
2013
-
A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome..
9.
2013
-
Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4..
9.
2013
-
Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors..
9.
2013
-
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk..
9.
2013
-
Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk..
9.
2013
-
Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1..
9.
2013
-
MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus..
9.
2013
-
Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production..
9.
2013
-
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies..
9.
2013
-
Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity..
9.
2013
-
The telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structures..
9.
2013
-
Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction..
8.
2012
-
Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information..
8.
2012
-
A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast..
8.
2012
-
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway..
8.
2012
-
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia..
8.
2012
-
Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis..
8.
2012
-
Patterns of ancestry, signatures of natural selection, and genetic association with stature in Western African pygmies..
8.
2012
-
Genomic analysis of the hydrocarbon-producing, cellulolytic, endophytic fungus Ascocoryne sarcoides..
8.
2012
-
Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease..
8.
2012
-
Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants..
8.
2012
-
Checkpoints in a yeast differentiation pathway coordinate signaling during hyperosmotic stress..
8.
2012
-
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection..
7.
2011
-
Discovery of sexual dimorphisms in metabolic and genetic biomarkers..
7.
2011
-
Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility..
7.
2011
-
Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis..
7.
2011
-
Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis..
6.
2010
-
Common genetic variants and modification of penetrance of BRCA2-associated breast cancer..
6.
2010
-
Whole-genome SNP association in the horse: identification of a deletion in myosin Va responsible for Lavender Foal Syndrome..
6.
2010
-
A mouse model of the human Fragile X syndrome I304N mutation..
5.
2009
-
Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase..
5.
2009
-
An African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans..
5.
2009
-
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum..
4.
2008
-
MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis..
4.
2008
-
Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression..
4.
2008
-
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics..
4.
2008
-
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci..
4.
2008
-
Adaptive gene expression divergence inferred from population genomics..
3.
2007
-
Reductive genome evolution from the mother of Rickettsia..
3.
2007
-
Retraction: an African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans..
5.
2009
-
Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.
2016
-
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.
2011
Identity
ISO Abbreviation
Linking ISSN
Electronic International Standard Serial Number (EISSN)