Ophthalmologic manifestations as the initial presentation of chronic myeloid leukemia: A review. Review uri icon

Overview

abstract

  • The presentation of chronic myeloid leukemia (CML) can be variable and related to the phase of the disease. It can manifest a wide range of symptoms and signs; ocular involvement is reported in patients with leukemia at the time of diagnosis. We describe ophthalmic manifestations as an initial presentation in patients with CML. We identified 38 publications between 1971 and 2020 describing ocular manifestations in CML. Ophthalmic problems occur either from direct or indirect infiltration of neoplastic cells or from secondary causes. Although nearly all ocular structures may be affected, leukemic retinopathy is the most frequent clinical manifestation. Others include iris infiltration, anterior uveitis, hypopyon, exudative/serous retinal detachment, and optic nerve infiltration.

publication date

  • July 10, 2021

Research

keywords

  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive
  • Ophthalmology
  • Retinal Detachment
  • Retinal Diseases

Identity

Scopus Document Identifier

  • 85111686042

Digital Object Identifier (DOI)

  • 10.1016/j.survophthal.2021.07.001

PubMed ID

  • 34252423