selected publications
- APOE3 - R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition. 2024 GET IT
- Human iPSC 4R tauopathy model uncovers modifiers of tau propagation. Cell. 2024 Academic Article GET IT
- ScISOr-ATAC reveals convergent and divergent splicing and chromatin specificities between matched cell types across cortical regions, evolution, and in Alzheimer's Disease. 2024 GET IT
- Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model. 2024 GET IT
- DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity. 2023 GET IT
- DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity. 2023 GET IT
- Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging. 2023 GET IT
- Human iPSC 4R tauopathy model uncovers modifiers of tau propagation. 2023 GET IT
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Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Nature neuroscience.
2023
Academic Article
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Times cited: 32 -
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
Nature communications.
2022
Academic Article
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Times cited: 96 -
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue.
Nature biotechnology.
2022
Academic Article
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Times cited: 35 -
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
Science advances.
2022
Academic Article
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Times cited: 16 -
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
Science translational medicine.
2021
Academic Article
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Times cited: 41 - Differential adhesion regulates neurite placement via a retrograde zippering mechanism. eLife. 2021 Academic Article GET IT
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A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.
eLife.
2020
Academic Article
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Times cited: 43 -
Cadherin preserves cohesion across involuting tissues during C. elegans neurulation.
eLife.
2020
Academic Article
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Times cited: 4 -
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.
Neuron.
2019
Academic Article
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Times cited: 76