Multiple cycles of high-dose doxorubicin and cyclophosphamide with G- CSF mobilized peripheral blood progenitor cell support in patients with metastatic breast cancer Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Breast Neoplasms
  • Hematopoietic Stem Cell Mobilization
  • Hematopoietic Stem Cell Transplantation

abstract

  • The MTD of this three cycle high-dose regimen was doxorubicin 110 mg/m2 and cyclophosphamide 4 g/m2 with mucositis and cystitis being dose-limiting toxicities. Although the primary aim was not the evaluation of antitumour effect, this high-dose regimen does not appear to provide an improvement of treatment results in comparison with our previous study with the same drugs at moderately high-dosages without stem cell support.

publication date

  • October 1997

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1023/A:1008259518263

PubMed ID

  • 9402167

Additional Document Info

start page

  • 957

end page

  • 62

volume

  • 8

number

  • 10