Cytarabine with high-dose mitoxantrone induces rapid complete remissions in adult acute lymphoblastic leukemia without the use of vincristine or prednisone Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma

abstract

  • This dose-intense induction regimen produced a high incidence of CRs with acceptable toxicity without the use of vincristine or corticosteroids. Comparisons with our prior vincristine/prednisone-based induction regimen (the L-20 protocol) suggest that patients treated on the current study were more likely to achieve a CR and that they achieved this remission earlier than patients treated with a traditional four-drug (vincristine, prednisone, doxorubicin, and cyclophosphamide) induction regimen.

publication date

  • September 22, 1996

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8823326

Additional Document Info

start page

  • 2480

end page

  • 5

volume

  • 14

number

  • 9