Comparison of cardiac structure and function in American Indians with and without the metabolic syndrome (the Strong Heart Study) Academic Article Article uri icon


MeSH Major

  • Cardiovascular Diseases
  • Diabetes Mellitus, Type 2
  • Hypertrophy, Left Ventricular


  • The metabolic syndrome (MS) is linked to cardiovascular risk. Recently, the Adult Treatment Panel (ATP) III provided new criteria for the definition of the MS. We analyzed the impact of the MS on cardiac structure and function and the independent association of the 5 different components of the ATP III-defined MS with cardiac markers of preclinical disease. Echocardiographic examination was performed in 612 nondiabetic participants with ATP III-defined MS and in 824 participants without the MS. Participants with the MS were more often women (p <0.001) and had similar ages compared with those without the MS. After controlling for confounders, participants with the MS had greater left ventricular (LV) dimension, mass, and relative wall thickness, and left atrial diameter (all p

publication date

  • January 2004



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1016/j.amjcard.2003.09.009

PubMed ID

  • 14697463

Additional Document Info

start page

  • 40

end page

  • 4


  • 93


  • 1