Radioembolisation of hepatocellular carcinoma with 90-yttrium resin particles
Mitral Valve Insufficiency
In 19 patients (34 applications) radioembolisation with Y-90 resin particles applied superselectively with microcatheters was carried out as a palliative treatment of liver cell carcinoma. The calculations of tumour dose and of exposure to the liver parenchyma and lung were made following angioscintigraphy with 99mTc-MAP. In 27 patients the tumour dose was between 50 and 470 Gy, in 5 patients < 50 Gy and in 2 patients > 800 Gy. The adjacent liver parenchyma was exposed to 13% of the targeted tumour dose (mean 34 Gy). The lung shunt in 31 applications was between 0 and 8%, in three instances between 12 and 14%. Complications due to shunt or reflux were observed in 2 patients. Small solitary hypervascularised tumours showed the most improvement (high dose/low-volume embolisation). In multisegmental/lobar tumours, radioembolisation with smaller doses ( < 100 Gy) showed good palliative effects (medium dose/limited-volume embolisation). © 1995 Springer-Verlag.
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