Intraductal carcinoma of the prostate is an aggressive form of invasive carcinoma and should be graded Review uri icon

Overview

MeSH Major

  • Angiomyolipoma
  • Kidney Neoplasms

abstract

  • Infiltration of the prostatic ducts by prostatic adenocarcinoma occurs relatively frequently, being most commonly associated with high grade disease. It is now recognised that intraductal carcinoma of the prostate (IDCP) has an associated poor prognosis and this is reflected in its histological, molecular and immunohistochemical features. The current recommendation of the World Health Organization is that IDCP not be taken into consideration when grading prostate adenocarcinoma. It is apparent that Gleason did not differentiate between IDCP and stromal invasive carcinoma when developing and validating his grading system, and recent studies suggest that the incorporation of IDCP grading into the overall grading of the specimen provides additional prognostic information.

authors

publication date

  • February 2020

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.pathol.2019.11.001

PubMed ID

  • 31843189

Additional Document Info

start page

  • 192

end page

  • 196

volume

  • 52

number

  • 2