Diabetic muscle infarction: Often misdiagnosed and mismanaged Academic Article uri icon


MeSH Major

  • Cornea
  • Microscopy, Confocal
  • Nerve Fibers
  • Peripheral Nervous System Diseases


  • © 2019 Verjee et al. A patient with type 2 diabetes, retinopathy, neuropathy, and nephropathy presented with severe right distal thigh pain, which awoke him from sleep. He was diagnosed with musculoskeletal pain and discharged home. Two days later, the severity of pain increased in his right thigh and, subsequently, he developed pain in the proximal lateral aspect of his left thigh, for which he returned to hospital. He had elevated creatine kinase and myoglobin levels. An ultrasound of the right thigh identified a loss of definition of the normal muscular striations and subcutaneous edema. On MRI, the axial STIR image demonstrated extensive T2 hyperintensity in the right vastus medialis and left vastus lateralis, consistent with the diagnosis of diabetic muscle infarction (DMI). This presentation emphasizes the need for a thorough patient history and physical examination, and the importance of directed imaging for the prompt diagnosis of DMI.

publication date

  • January 2019



  • Academic Article


Digital Object Identifier (DOI)

  • 10.2147/DMSO.S185839

Additional Document Info

start page

  • 285

end page

  • 290


  • 12