About face: Molecular aberrations in head and neck mucosal melanomas
Vascular Endothelial Growth Factor C
© 2019 American Association for Cancer Research. Detailed molecular characterization of a large cohort of mucosal melanomas, most arising from head and neck primaries, suggests that chromosomal translocations and other complex rearrangements have prognostic importance. CDK4 amplification is a frequent event in these rare tumors, and CDK4/6 inhibition may represent a rational clinical trial strategy.
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