About face: Molecular aberrations in head and neck mucosal melanomas Comment uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Endothelial Cells
  • Receptors, CCR7
  • Vascular Endothelial Growth Factor C

abstract

  • © 2019 American Association for Cancer Research. Detailed molecular characterization of a large cohort of mucosal melanomas, most arising from head and neck primaries, suggests that chromosomal translocations and other complex rearrangements have prognostic importance. CDK4 amplification is a frequent event in these rare tumors, and CDK4/6 inhibition may represent a rational clinical trial strategy.

publication date

  • June 15, 2019

Research

keywords

  • Comment

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-19-0658

PubMed ID

  • 30952641

Additional Document Info

start page

  • 3473

end page

  • 3475

volume

  • 25

number

  • 12