T2D Risk Genes: Exome Sequencing Goes Straight to the Source Academic Article uri icon

Overview

MeSH Major

  • Cell Proliferation
  • Glucose
  • Insulin-Secreting Cells

abstract

  • Genome-wide association studies have identified hundreds of genomic variants associated with human T2D risk, but translating such findings to clinically useful information has proved challenging. A new study in Nature (Flannick et al., 2019) breaks this gridlock, using direct exome sequencing to identify functional coding variants, providing critical complementary gene-level information.

publication date

  • July 2, 2019

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.cmet.2019.06.010

PubMed ID

  • 31269421

Additional Document Info

start page

  • 10

end page

  • 11

volume

  • 30

number

  • 1