Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study Academic Article uri icon

Overview

MeSH Major

  • Neoplastic Cells, Circulating
  • Prostatic Neoplasms, Castration-Resistant
  • Receptors, Androgen

abstract

  • Detection of AR-V7 in CTCs by two blood-based assays is independently associated with shorter PFS and OS with abiraterone or enzalutamide, and such men with mCRPC should be offered alternative treatments.

publication date

  • May 2019

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC6494355

Digital Object Identifier (DOI)

  • 10.1200/JCO.18.01731

PubMed ID

  • 30865549

Additional Document Info

start page

  • 1120

end page

  • 1129

volume

  • 37

number

  • 13