Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma Academic Article uri icon

Overview

MeSH Major

  • Androgen Antagonists
  • Androgen Receptor Antagonists
  • Bone Neoplasms
  • Castration
  • Prostatic Neoplasms
  • Thiohydantoins

abstract

  • © 2019, The Author(s). A systematic study of the stability of a set of cephalosporins in mouse plasma reveals that cephalosporins lacking an acidic moiety at C-2 may be vulnerable to β-lactam cleavage in mouse plasma.

publication date

  • January 2019

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1038/s41429-019-0167-y