Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer
Carcinoma, Transitional Cell
Urinary Bladder Neoplasms
MSI-H/MMR-D is predictive of LS across a much broader tumor spectrum than currently appreciated. Given implications for cancer surveillance and prevention measures in affected families, these data support germline genetic assessment for LS for patients with an MSI-H/MMR-D tumor, regardless of cancer type or family cancer history.