Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Carboplatin
  • Carcinoma, Transitional Cell
  • Cisplatin
  • Nomograms
  • Urologic Neoplasms

abstract

  • UTUC and UCB exhibit significant differences in the prevalence of common genomic alterations. In individual patients with a history of both tumors, UCB and UTUC were always clonally related. Genomic characterization of UTUC provides information regarding the risk of bladder recurrence and can identify tumors associated with Lynch syndrome.

publication date

  • February 2019

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC6359971

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-18-2039

PubMed ID

  • 30352907

Additional Document Info

start page

  • 967

end page

  • 976

volume

  • 25

number

  • 3