Preclinical Pharmacology in the Rhesus Monkey of CW 1759-50, a New Ultra-short Acting Nondepolarizing Neuromuscular Blocking Agent, Degraded and Antagonized by L-Cysteine Academic Article uri icon

Overview

MeSH Major

  • Aging
  • Atrial Fibrillation
  • Heart Atria
  • Kv Channel-Interacting Proteins
  • Sodium-Hydrogen Antiporter

abstract

  • CW 1759-50, similar to gantacurium, is an ultra-short acting neuromuscular blocking agent, antagonized by L-cysteine, in the monkey. The circulatory effects, however, are much reduced in comparison with gantacurium, suggesting a trial in humans.

publication date

  • November 2018

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1097/ALN.0000000000002408

PubMed ID

  • 30212413

Additional Document Info

start page

  • 970

end page

  • 988

volume

  • 129

number

  • 5