Break-induced replication sparks CGG-repeat instability Academic Article uri icon

Overview

MeSH Major

  • Cell Cycle Proteins
  • Chromatin
  • DNA Helicases

abstract

  • © 2018, The Publisher. The mechanism underlying CCG-repeat expansions in patients with fragile X premutation is not well understood. Using a new experimental system in mammalian cells, a study in this issue reports that break-induced replication has a role in CGG-repeat instability.

publication date

  • August 2018

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1038/s41594-018-0103-z

PubMed ID

  • 30061599

Additional Document Info

start page

  • 643

end page

  • 644

volume

  • 25

number

  • 8