Identifying prevalence and risk factors for metformin non-persistence: A retrospective cohort study using an electronic health record
Arthroplasty, Replacement, Hip
Arthroplasty, Replacement, Knee
These data support the routine prescribing of low starting doses of metformin as a tool to improve persistence. In this study setting, many providers routinely used ER metformin as an initial treatment; while this practice may have benefits, it deserves more rigorous study to assess whether increased costs are justified.