Social regulation of insulin signaling and the evolution of eusociality in ants Academic Article uri icon

Overview

MeSH Major

  • Bees
  • Hierarchy, Social
  • Infertility
  • Quantitative Trait Loci

abstract

  • © 2018 Academic Press. All rights reserved. Queens and workers of eusocial Hymenoptera are considered homologous to the reproductive and brood care phases of an ancestral subsocial life cycle. However, the molecular mechanisms underlying the evolution of reproductive division of labor remain obscure. Using a brain transcriptomics screen, we identified a single gene, insulin-like peptide 2 (ilp2), which is always up-regulated in ant reproductives, likely because they are better nourished than their nonreproductive nestmates. In clonal raider ants (Ooceraea biroi), larval signals inhibit adult reproduction by suppressing ilp2, thus producing a colony reproductive cycle reminiscent of ancestral subsociality. However, increasing ILP2 peptide levels overrides larval suppression, thereby breaking the colony cycle and inducing a stable division of labor. These findings suggest a simple model for the origin of ant eusociality via nutritionally determined reproductive asymmetries potentially amplified by larval signals.

publication date

  • July 27, 2018

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1126/science.aar5723

PubMed ID

  • 30049879

Additional Document Info

start page

  • 398

end page

  • 402

volume

  • 361

number

  • 6400