Cancer-Specific Splicing Changes and the Potential for Splicing-Derived Neoantigens Article uri icon

Overview

MeSH Major

  • Ascorbic Acid
  • DNA-Binding Proteins
  • Leukemia, Myeloid, Acute
  • Myelodysplastic Syndromes
  • Proto-Oncogene Proteins
  • Vitamins

abstract

  • © 2018 Elsevier Inc. In this issue of Cancer Cell, Kahles et al. perform a comprehensive analysis of RNA splicing across cancer types and identify novel correlations between genetic alterations and splicing in cancer. In addition, they identify that tumor-specific splicing has the potential to generate a large new class of tumor-specific neoantigens. In this issue of Cancer Cell, Kahles et al. perform a comprehensive analysis of RNA splicing across cancer types and identify novel correlations between genetic alterations and splicing in cancer. In addition, they identify that tumor-specific splicing has the potential to generate a large new class of tumor-specific neoantigens.

publication date

  • January 2018

Research

keywords

  • Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/j.ccell.2018.07.008

Additional Document Info