Management of Patients with Acute Methotrexate Nephrotoxicity with High-Dose Leucovorin Academic Article uri icon

Overview

MeSH Major

  • Bone Neoplasms
  • Neoplasm Recurrence, Local
  • Osteosarcoma

abstract

  • Patients who had 100 episodes of HDMTX-associated acute kidney injury were treated with a strategy that only included usual supportive measures and high-dose leucovorin. No deaths were directly attributed to complications related to HDMTX. Glucarpidase, an expensive drug, may not be necessary for a significant number of patients.

publication date

  • July 2018

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/phar.2145

PubMed ID

  • 29863765

Additional Document Info

start page

  • 714

end page

  • 724

volume

  • 38

number

  • 7