Thalamic Glioblastoma: Clinical Presentation, Management Strategies, and Outcomes
Gene Expression Regulation, Neoplastic
Receptor, Epidermal Growth Factor
The overall survival of patients with thalamic glioblastoma is comparable to unresectable lobar supratentorial GBMs. Younger patients and those with good presenting functional status had improved survival. Midbrain involvement by the tumor is not a negative prognostic factor. Improved therapies are needed, and patients should be considered for early trial involvement and aggressive upfront therapy.