Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: Results of Alliance N0874/ABTC 02 Academic Article uri icon

Overview

MeSH Major

  • Arteries
  • Microsurgery
  • Perforator Flap
  • Thigh
  • Vascular Surgical Procedures

abstract

  • Vorinostat combined with standard chemoradiation had acceptable tolerability in newly diagnosed glioblastoma. Although the primary efficacy endpoint was not met, vorinostat sensitivity and resistance signatures could facilitate patient selection in future trials.

publication date

  • 2019

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5909661

Digital Object Identifier (DOI)

  • 10.1093/neuonc/nox161

PubMed ID

  • 29016887

Additional Document Info

start page

  • 546

end page

  • 556

volume

  • 20

number

  • 4