Use of Digital Rectal Examination as an Adjunct to Prostate Specific Antigen in the Detection of Clinically Significant Prostate Cancer Academic Article uri icon


MeSH Major

  • Carcinoma, Renal Cell
  • Kidney Neoplasms
  • Laparoscopy
  • Nephrectomy
  • Robotic Surgical Procedures


  • Digital rectal examination demonstrated prognostic usefulness when prostate specific antigen was greater than 3 ng/ml, limited usefulness for less than 2 ng/ml and marginal usefulness for 2 to 3 ng/ml. These findings support the restriction of digital rectal examination to men with higher prostate specific antigen as a reflex test to improve specificity. It should not be used as a primary screening modality to improve sensitivity.

publication date

  • January 2018



  • Academic Article



  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.juro.2017.10.021

PubMed ID

  • 29061540

Additional Document Info