Diabetic neuropathy and painful diabetic neuropathy: Cinderella complications in South East Asia Article Report uri icon


MeSH Major

  • Cornea
  • Microscopy, Confocal
  • Nerve Fibers
  • Peripheral Nervous System Diseases


  • © 2018, Pakistan Medical Association. All rights reserved. The most common and debilitating microvascular complication of diabetes is diabetic peripheral neuropathy (DPN), affecting 50-90% of people with diabetes. The major manifestations of DPN are painful (pDPN) and painless diabetic peripheral neuropathy. Painful symptoms, occur in the feet and are worse at night and whilst they alert both the patient and physician, are often misdiagnosed and mismanaged. The devastating presentation of painless neuropathy with loss of sensation is foot ulceration and Charcot foot. The explosion of diabetes, especially in the South East Asian (SEA) region will result in an increasing prevalence of both painful and painless diabetic peripheral neuropathy. PubMed, EMBASE, Medline and Google Scholar databases were searched between 1990 and 2017. This highlights the widely varying prevalence of DPN and pDPN in the World Health Organization (WHO) defined SEA countries and the dearth of published studies, especially in pDPN. We believe this will provide new direction for future research on DPN in the SEA region.

publication date

  • January 2018



  • Report


PubMed ID

  • 29371725

Additional Document Info

start page

  • 85

end page

  • 89


  • 68


  • 1