C cell and follicular epithelial cell precursor lesions of the thyroid Review uri icon

Overview

MeSH Major

  • Precancerous Conditions
  • Thyroid Diseases
  • Thyroid Gland
  • Thyroid Neoplasms

abstract

  • - Although the preneoplastic nature of C-cell hyperplasia in the setting of familial medullary thyroid carcinoma is well recognized, the preneoplastic nature/malignant potential of reactive/physiologic C-cell hyperplasia and its role in the development of sporadic, medullary thyroid carcinoma is still unclear. Current data suggest that benign follicular lesions may have malignant potential, and there may be a multifocal progression from benign to malignant. Atypical follicular lesions in the background of chronic lymphocytic thyroiditis may represent dysplastic or premalignant lesions.

publication date

  • December 2017

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.5858/arpa.2016-0399-RA

PubMed ID

  • 28644684

Additional Document Info

start page

  • 1646

end page

  • 1652

volume

  • 141

number

  • 12