Integrating nanomedicine and imaging Review uri icon

Overview

MeSH Major

  • Fluorescent Dyes
  • Nanoparticles
  • Neoplasms
  • Positron-Emission Tomography
  • Zirconium

abstract

  • Biomedical engineering and its associated disciplines play a pivotal role in improving our understanding and management of disease. Motivated by past accomplishments, such as the clinical implementation of coronary stents, pacemakers or recent developments in antibody therapies, disease management now enters a new era in which precision imaging and nanotechnology-enabled therapeutics are maturing to clinical translation. Preclinical molecular imaging increasingly focuses on specific components of the immune system that drive disease progression and complications, allowing the in vivo study of potential therapeutic targets. The first multicentre trials highlight the potential of clinical multimodality imaging for more efficient drug development. In this perspective, the role of integrating engineering, nanotechnology, molecular imaging and immunology to yield precision medicine is discussed.This article is part of the themed issue 'Challenges for chemistry in molecular imaging'.

publication date

  • November 28, 2017

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC5647268

Digital Object Identifier (DOI)

  • 10.1098/rsta.2017.0110

PubMed ID

  • 29038380

Additional Document Info

volume

  • 375

number

  • 2107