Usual interstitial pneumonia can be detected in transbronchial biopsies using machine learning Academic Article uri icon

Overview

MeSH Major

  • Lung Diseases, Interstitial
  • Pulmonary Fibrosis

abstract

  • We demonstrate proof of principle that genomic analysis and machine learning improves the utility of TBB for the diagnosis of UIP, with greater sensitivity and specificity than pathology in TBB alone. Combining multiple individual subject samples results in increased test accuracy over single sample testing. This approach requires validation in an independent cohort of subjects before application in the clinic.

publication date

  • November 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1513/AnnalsATS.201612-947OC

PubMed ID

  • 28640655

Additional Document Info

start page

  • 1646

end page

  • 1654

volume

  • 14

number

  • 11