Abnormal Remodeling of Subcutaneous Small Arteries Is Associated With Early Diastolic Impairment in Metabolic Syndrome Academic Article uri icon

Overview

MeSH Major

  • Arteries
  • Metabolic Syndrome X
  • Obesity
  • Subcutaneous Fat
  • Vascular Remodeling
  • Ventricular Dysfunction, Left
  • Ventricular Function, Left

abstract

  • Although the small arteries studied were not cardiac in origin, our results support a role for small artery remodeling in the development of diastolic dysfunction in humans. Further direct examination of the structure and function of the myocardial resistance vasculature is now warranted, to elucidate the temporal association between metabolic risk factors, small artery injury, and diastolic impairment.

publication date

  • April 11, 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5532992

Digital Object Identifier (DOI)

  • 10.1161/JAHA.116.004603

PubMed ID

  • 28400366

Additional Document Info

volume

  • 6

number

  • 4