Clinical and Genetic Associations of Objectively Identified Interstitial Changes in Smokers Academic Article uri icon

Overview

MeSH Major

  • DNA
  • Lung Diseases, Interstitial
  • Mucin-5B
  • Polymorphism, Genetic
  • Smoking

abstract

  • Objective interstitial changes on CT scans were associated with impaired lung function, worse quality of life, increased mortality, and more copies of a MUC5B promoter polymorphism, suggesting that these changes may be a marker of susceptibility to smoking-related lung injury, detectable even in those who are healthy by other measures.

publication date

  • October 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.chest.2017.04.185

PubMed ID

  • 28506611

Additional Document Info

start page

  • 780

end page

  • 791

volume

  • 152

number

  • 4