Sex differences in Alzheimer risk: Brain imaging of endocrine vs chronologic aging Academic Article uri icon

Overview

MeSH Major

  • Aging
  • Alzheimer Disease
  • Brain
  • Sex Characteristics

abstract

  • Multimodality brain imaging indicates sex differences in development of the AD endophenotype, suggesting that the preclinical AD phase is early in the female aging process and coincides with the endocrine transition of perimenopause. These data indicate that the optimal window of opportunity for therapeutic intervention in women is early in the endocrine aging process.

publication date

  • September 26, 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5652968

Digital Object Identifier (DOI)

  • 10.1212/WNL.0000000000004425

PubMed ID

  • 28855400

Additional Document Info

start page

  • 1382

end page

  • 1390

volume

  • 89

number

  • 13