Clinical and Molecular Evidence of Atovaquone and Azithromycin Resistance in Relapsed Babesia microti Infection Associated with Rituximab and Chronic Lymphocytic Leukemia Academic Article uri icon

Overview

MeSH Major

  • Anti-Bacterial Agents
  • Bacteremia
  • Carbapenems
  • Enterobacteriaceae

abstract

  • Babesiosis treatment failures with standard therapy have been reported, but the molecular mechanisms are not well understood. We describe the emergence of atovaquone and azithromycin resistance associated with mutations in the binding regions of the target proteins of both drugs during treatment of an immunosuppressed patient with relapsing babesiosis.

publication date

  • October 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1093/cid/cix477

PubMed ID

  • 28541469

Additional Document Info

start page

  • 1222

end page

  • 1225

volume

  • 65

number

  • 7