Activated ovarian endothelial cells promote early follicular development and survival Academic Article uri icon

Overview

MeSH Major

  • Cell Differentiation
  • Cellular Reprogramming
  • Endothelium
  • Hematopoietic Stem Cells
  • T-Lymphocytes

abstract

  • In vitro development of early follicles necessitates a complex interplay of growth factors and signals required for development. Endothelial cells (ECs) may elaborate essential "angiocrine factors" involved in organ regeneration. We demonstrate that co-culture with ovarian ECs enables culture of primary and early secondary mouse ovarian follicles.

publication date

  • September 19, 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5605973

Digital Object Identifier (DOI)

  • 10.1186/s13048-017-0354-z

PubMed ID

  • 28927438

Additional Document Info

start page

  • 64

volume

  • 10

number

  • 1