Imaging and management of fetuses and neonates with alloimmune thrombocytopenia Review uri icon


MeSH Major

  • Fetal Diseases
  • Intracranial Hemorrhages
  • Thrombocytopenia, Neonatal Alloimmune


  • Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is the most common cause of severe neonatal thrombocytopenia and intracranial bleeding in term newborns. Intracranial hemorrhage (ICH) commonly results in death or severe, lasting neurologic disability. The timing of ICH is also important for management of the next affected pregnancy in cases of FNAIT. This manuscript reviews the advantages and disadvantages of the different radiologic methodologies to identify and characterize ICH. It discusses the limits of ultrasound and the advantages of magnetic resonance imaging allowing avoidance of the radiation associated with computed tomography (CT) scans.

publication date

  • January 2017



  • Review



  • eng

Digital Object Identifier (DOI)

  • 10.1002/pbc.26690

PubMed ID

  • 28675682

Additional Document Info