Associations of Age and Sex with Marfan Phenotype: The National Heart, Lung, and Blood Institute GenTAC (Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions) Registry Academic Article uri icon

Overview

MeSH Major

  • Arsenic
  • Diabetes Mellitus, Type 2
  • Indians, North American
  • Peripheral Arterial Disease

abstract

  • Pulmonary, skeletal, and aortic complications, but not other phenotypic features, are more prevalent in adults than children in Marfan syndrome. Aortic aneurysms and prophylactic aortic surgery are more common in men. Aortic dissection, commonly type B, occurs in an appreciable proportion of Marfan patients, especially in men and after previous prophylactic aortic root replacement.

publication date

  • June 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5500868

Digital Object Identifier (DOI)

  • 10.1161/CIRCGENETICS.116.001647

PubMed ID

  • 28600386

Additional Document Info

volume

  • 10

number

  • 3