Relationships among cortical glutathione levels, brain amyloidosis, and memory in healthy older adults investigated in vivo with 1H-MRS and Pittsburgh compound-B PET Academic Article uri icon

Overview

MeSH Major

  • Cognition Disorders
  • Hydrocephalus, Normal Pressure
  • Neuropsychological Tests
  • Psychomotor Disorders

abstract

  • This study found an association between cortical glutathione levels and brain amyloidosis in healthy older adults, suggesting a potential role for (1)H-MR spectroscopy measures of glutathione as a noninvasive biomarker of early Alzheimer disease pathogenesis.

publication date

  • June 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5471116

Digital Object Identifier (DOI)

  • 10.3174/ajnr.A5143

PubMed ID

  • 28341718

Additional Document Info

start page

  • 1130

end page

  • 1137

volume

  • 38

number

  • 6