Molecular definitions of autophagy and related processes Review uri icon

Overview

MeSH Major

  • Autophagy
  • Terminology as Topic

abstract

  • Over the past two decades, the molecular machinery that underlies autophagic responses has been characterized with ever increasing precision in multiple model organisms. Moreover, it has become clear that autophagy and autophagy-related processes have profound implications for human pathophysiology. However, considerable confusion persists about the use of appropriate terms to indicate specific types of autophagy and some components of the autophagy machinery, which may have detrimental effects on the expansion of the field. Driven by the overt recognition of such a potential obstacle, a panel of leading experts in the field attempts here to define several autophagy-related terms based on specific biochemical features. The ultimate objective of this collaborative exchange is to formulate recommendations that facilitate the dissemination of knowledge within and outside the field of autophagy research.

authors

publication date

  • January 2017

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC5494474

Digital Object Identifier (DOI)

  • 10.15252/embj.201796697

PubMed ID

  • 28596378

Additional Document Info

start page

  • 1811

end page

  • 1836