A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes Academic Article uri icon

Overview

MeSH Major

  • Diabetes Mellitus, Type 1

abstract

  • More than 50% of children and adolescents with new-onset T1D do not undergo partial clinical remission and are thus at an increased risk for long-term complications of diabetes mellitus. A predictive model comprising of bicarbonate <15 mg/dL, age <5y, female sex, and >3 diabetes-associated autoantibodies has 73% power for correctly predicting non-remission in children and adolescents with new-onset T1D. Early identification of these non-remitters may guide the institution of targeted therapy to limit dysglycemia and reduce the prevalence of long-term deleterious complications.

publication date

  • May 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5411061

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0176860

PubMed ID

  • 28459844

Additional Document Info

start page

  • e0176860

volume

  • 12

number

  • 5