Hippocampal-sparing and target volume coverage in treating 3 to 10 brain metastases: A comparison of Gamma Knife, single-isocenter VMAT, CyberKnife, and TomoTherapy stereotactic radiosurgery Academic Article uri icon

Overview

MeSH Major

  • Brain Injuries
  • Erythropoietin
  • Neuroprotective Agents
  • Radiosurgery

abstract

  • Hippocampi play an important role in memory, and sparing of these structures in whole brain radiation can improve neurocognitive outcomes. The hippocampi are not routinely spared when using stereotactic radiosurgery. We evaluated the incidental dose to the hippocampi when treating multiple brain metastases and sought to examine if hippocampal sparing is feasible without detriment to target coverage. We found that hippocampal sparing is possible without affecting coverage or conformality in most cases across treatment platforms.

publication date

  • May 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.prro.2017.01.012

PubMed ID

  • 28477798

Additional Document Info

start page

  • 183

end page

  • 189

volume

  • 7

number

  • 3