A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis Academic Article uri icon

Overview

MeSH Major

  • Arthritis, Rheumatoid
  • HLA-DRB1 Chains
  • Phosphoproteins
  • gamma-Glutamyltransferase

abstract

  • This first RA GWAS in Arab populations confirms that established HLA-region and known RA risk alleles contribute strongly to the risk and severity of disease in some Arab groups, suggesting that the genetic architecture of RA is similar across ethnic groups. Moreover, this study identified 2 novel RA risk loci in Arabs, offering further population-specific insights into the pathophysiology of RA.

publication date

  • May 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/art.40051

PubMed ID

  • 28118524

Additional Document Info

start page

  • 976

end page

  • 985

volume

  • 69

number

  • 5