The toxicity and efficacy of concomitant chemoradiotherapy in patients aged 70 years and older with oropharyngeal carcinoma in the intensity-modulated radiotherapy era Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Squamous Cell
  • Chemoradiotherapy
  • Oropharyngeal Neoplasms

abstract

  • Toxicity from CCRT remains a challenge for older adults with OPSCC. Herein, the authors found no evidence that this toxicity was mitigated by treatment with cetuximab. Nevertheless, a subset of patients aged ≥70 years appear to tolerate cisplatin-based treatment with acceptable toxicity and excellent outcomes. Further identification of this patient subgroup is crucial to optimize therapy for older patients with OPSCC. Cancer 2017;123:1345-1353. © 2016 American Cancer Society.

publication date

  • April 15, 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5384883

Digital Object Identifier (DOI)

  • 10.1002/cncr.30495

PubMed ID

  • 27984656

Additional Document Info

start page

  • 1345

end page

  • 1353

volume

  • 123

number

  • 8