Juvenile dermatomyositis/polymyositis and lymphoma Review uri icon

Overview

MeSH Major

  • Immunologic Factors
  • Lymphoma
  • Myositis

abstract

  • © 2017 Elsevier B.V.In patients with juvenile dermatomyositis/polymyositis (JDM/PM), malignancy is a rare phenomenon. An extensive workup for neoplastic disease is not routinely indicated, but should be considered if unusual physical findings are noted at JDM/PM diagnosis or during follow-up period. The objective of this literature review was to assess for any association between, and disease profile of, JDM/PM and lymphoma in childhood. Risk determinants of the possible development of lymphoma in the pediatric population with JDM/PM appear to be the degree and duration of inflammatory activity with chronic B-cell activation and/or antigen stimulation; a paraneoplastic relationship is unlikely.

publication date

  • June 15, 2017

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.jns.2017.03.033

PubMed ID

  • 28477693

Additional Document Info

start page

  • 19

end page

  • 24

volume

  • 377