Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Genes, BRCA1
  • Genes, BRCA2
  • Mutation
  • Ovarian Neoplasms

abstract

  • BC and OC PRS are predictive of cancer risk in BRCA1 and BRCA2 carriers. Incorporation of the PRS into risk prediction models has promise to better inform decisions on cancer risk management.

publication date

  • July 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5408990

Digital Object Identifier (DOI)

  • 10.1093/jnci/djw302

PubMed ID

  • 28376175

Additional Document Info

volume

  • 109

number

  • 7