Functional disorders of swallowing Review uri icon


MeSH Major

  • Deglutition Disorders
  • Psychophysiologic Disorders


  • Swallowing involves complex coordination of the neuromuscular anatomy and physiology of the oropharynx and esophagus, controlled by the enteric and central nervous systems. Dysphagia is classified as either oropharyngeal or esophageal and results from mechanical or structural disturbances. Videofluoroscopy, fiberoptic endoscopic evaluation of swallowing, barium swallow, manometry, and endoscopy are common modalities utilized in diagnosis, but none is as important as a patient's history. Functional dysphagia is a diagnosis of exclusion and is based on Rome criteria. Its mechanism is unknown but potentially related to visceral hypersensitivity, inappropriate pain perception, or unidentified contraction abnormalities. Its management is mainly supportive; however, there is literature to suggest, but not confirm, benefit with the use of antidepressants. Continued understanding of functional dysphagia and other functional esophageal disorders, including globus sensation, will require further investigation into diagnostic algorithms and finding treatment methods.

publication date

  • January 2016



  • Review



  • eng

Digital Object Identifier (DOI)

  • 10.1016/B978-0-12-801772-2.00039-4

PubMed ID

  • 27719865

Additional Document Info

start page

  • 483

end page

  • 488


  • 139