The Gastric Microbiome and Its Influence on Gastric Carcinogenesis. Current Knowledge and Ongoing Research Review uri icon

Overview

MeSH Major

  • Cell Transformation, Viral
  • Epstein-Barr Virus Infections
  • Gastrointestinal Microbiome
  • Helicobacter Infections
  • Helicobacter pylori
  • Herpesvirus 4, Human
  • Stomach Neoplasms

abstract

  • © 2017 Elsevier Inc.Gastric malignancies are a leading cause of cancer-related death worldwide. At least 2 microbial species are currently linked to carcinogenesis and the development of cancer within the human stomach. These include the bacterium Helicobacter pylori and the Epstein-Barr virus. In recent years, there has been increasing evidence that within the human gastrointestinal tract it is not only pathogenic microbes that impact human health but also the corresponding autochthonous microbial communities. This article reviews the gastrointestinal microbiome as it relates primarily to mechanisms of disease and carcinogenesis within the upper gastrointestinal tract.

publication date

  • January 2017

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.hoc.2017.01.002

PubMed ID

  • 28501083

Additional Document Info