Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel Review uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Disease Management
  • Hematopoietic Stem Cell Transplantation
  • Leukemia, Myeloid, Acute

abstract

  • The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) in adults, published in 2010, has found broad acceptance by physicians and investigators caring for patients with AML. Recent advances, for example, in the discovery of the genomic landscape of the disease, in the development of assays for genetic testing and for detecting minimal residual disease (MRD), as well as in the development of novel antileukemic agents, prompted an international panel to provide updated evidence- and expert opinion-based recommendations. The recommendations include a revised version of the ELN genetic categories, a proposal for a response category based on MRD status, and criteria for progressive disease.

publication date

  • January 26, 2017

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC5291965

Digital Object Identifier (DOI)

  • 10.1182/blood-2016-08-733196

PubMed ID

  • 27895058

Additional Document Info

start page

  • 424

end page

  • 447

volume

  • 129

number

  • 4