A Pilot Study of a Multimodal Treatment Paradigm to Accelerate Drug Evaluations in Early-stage Metastatic Prostate Cancer Academic Article uri icon


MeSH Major

  • Cisplatin
  • Drug Resistance, Neoplasm
  • Neoplasms, Germ Cell and Embryonal


  • A sequentially applied multimodal treatment strategy can eliminate detectable disease in selected patients with metastatic spread at diagnosis. The end point of undetectable PSA after testosterone recovery should be considered when evaluating new approaches to rapidly set priorities for large-scale testing in early metastatic disease states and to shift the paradigm from palliation to cure.

publication date

  • August 5, 2016



  • Academic Article



  • eng

PubMed Central ID

  • PMC5468169

Digital Object Identifier (DOI)

  • 10.1016/j.urology.2016.10.044

PubMed ID

  • 27888148

Additional Document Info

start page

  • 164

end page

  • 172