Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer Academic Article uri icon

Overview

MeSH Major

  • Neoplastic Cells, Circulating
  • Prostatic Neoplasms, Castration-Resistant
  • Receptors, Androgen

abstract

  • The results validate CTC nuclear expression of AR-V7 protein in men with mCRPC as a treatment-specific biomarker that is associated with superior survival on taxane therapy over ARS-directed therapy in a clinical practice setting. Continued examination of this biomarker in prospective studies will further aid clinical utility.

publication date

  • November 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5206761

Digital Object Identifier (DOI)

  • 10.1001/jamaoncol.2016.1828

PubMed ID

  • 27262168

Additional Document Info

start page

  • 1441

end page

  • 1449

volume

  • 2

number

  • 11