Loss of Endothelial CXCR7 Impairs Vascular Homeostasis, and Cardiac Remodeling After Myocardial Infarction: Implications for Cardiovascular Drug Discovery Academic Article uri icon

Overview

MeSH Major

  • Genome-Wide Association Study
  • Homeostasis
  • Ventricular Remodeling

abstract

  • -CXCR7 represents a novel regulator of vascular homeostasis that functions in the endothelial compartment, with sufficient capacity to impact cardiac function and remodeling following MI. Activation of CXCR7 may have therapeutic potential for clinical restenosis after percutaneous coronary intervention and for heart remodeling after MI.

publication date

  • February 15, 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/CIRCULATIONAHA.116.023027

PubMed ID

  • 28154007

Additional Document Info