Influencing the tumor microenvironment: A Phase II study of copper depletion using tetrathiomolybdate in patients with breast cancer at high risk for recurrence and in preclinical models of lung metastases Academic Article uri icon

Overview

MeSH Major

  • Alpha Particles
  • Neovascularization, Pathologic

abstract

  • Tetrathiomolybdate is safe, well tolerated, and affects copper-dependent components of the tumor microenvironment. Biomarker-driven clinical trials in high risk for patients with recurrent breast cancer are warranted. Clin Cancer Res; 23(3); 666-76. ©2016 AACR.

publication date

  • February 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-16-1326

PubMed ID

  • 27769988

Additional Document Info

start page

  • 666

end page

  • 676

volume

  • 23

number

  • 3